| 구분 |
항목 |
기본단가 |
수량 |
금액 |
물질 필요량 |
| In vitro ADME |
Metabolic stability (% of remaining, 2종) |
300,000 |
|
|
1-2mg |
| Metabolic stability (% of remaining, 3종) |
400,000 |
|
|
| Metabolic stability (% of remaining, 5종) |
800,000 |
|
|
| Metabolic stability (T1/2, 1종) |
400,000 |
|
|
| CYP inhibition (% of inhibition, 5종) |
400,000 |
|
|
| CYP inhibition (IC50, 1종) |
400,000 |
|
|
| CYP inhibition ((IC50, 5종) |
1,200,000 |
|
|
| Plasma stability (% of remaining, 2종) |
300,000 |
|
|
| Plasma protein binding (%, 2종) |
400,000 |
|
|
| In vivo ADME |
In vivo rat PK (2경로) |
3,000,000 |
|
|
10 mg / kg 기준
20 mg |
| In vivo rat PK (1경로) |
1,500,000 |
|
|
10 mg / kg 기준
10 mg |
| In vivo mouse PK (2경로) |
3,000,000 |
|
|
10 mg / kg 기준
5 mg |
| In vivo mouse PK (1경로) |
1,500,000 |
|
|
10 mg / kg 기준
3 mg |
| 합계 |
|
|
